Complement evasion by human pathogens
نویسندگان
چکیده
منابع مشابه
Protease-dependent mechanisms of complement evasion by bacterial pathogens.
The human immune system has evolved a variety of mechanisms for the primary task of neutralizing and eliminating microbial intruders. As the first line of defense, the complement system is responsible for rapid recognition and opsonization of bacteria, presentation to phagocytes and bacterial cell killing by direct lysis. All successful human pathogens have mechanisms of circumventing the antib...
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Leptospirosis is a neglected infectious disease caused by spirochetes from the genus Leptospira. Pathogenic microorganisms, notably those which reach the blood circulation such as Leptospira, have evolved multiple strategies to escape the host complement system, which is important for innate and acquired immunity. Leptospira avoid complement-mediated killing through: (i) recruitment of host com...
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ژورنال
عنوان ژورنال: Nature Reviews Microbiology
سال: 2008
ISSN: 1740-1526,1740-1534
DOI: 10.1038/nrmicro1824